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Dermatologic conditions seen in end-stage renal disease
Katharine B Cordova1, Thomas J Oberg, Mohsin Malik
1Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
Seminars in Dialysis
|March 3, 2009
Summary
Skin changes in end-stage renal disease (ESRD) are varied. This review details common conditions like calciphylaxis and nephrogenic systemic fibrosis, covering their diagnosis and management.
Area of Science:
- Dermatology
- Nephrology
- Pathology
Background:
- End-stage renal disease (ESRD) is associated with diverse and significant cutaneous manifestations.
- These skin changes can impact patient quality of life and require specific diagnostic and management approaches.
Purpose of the Study:
- To review specific, frequently observed skin conditions in ESRD patients.
- To provide comprehensive information on the clinical features, histopathology, pathophysiology, differential diagnosis, and management of these entities.
Main Methods:
- Literature review focusing on common dermatological conditions in ESRD.
- Synthesis of information regarding clinical presentation, underlying mechanisms, and treatment strategies.
Main Results:
- Detailed review of perforating disorders, porphyria cutanea tarda, pseudoporphyria, calcinosis cutis, calciphylaxis, and nephrogenic systemic fibrosis.
- Emphasis on the unique morphology and diagnostic challenges of each condition.
Conclusions:
- Accurate identification and understanding of these specific skin conditions are crucial for effective patient care in ESRD.
- Management strategies should be tailored to the individual dermatological entity and patient's overall health status.
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