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Kinetic characterization of sulfasalazine transport by human ATP-binding cassette G2

Márton Jani1, Pál Szabó, Emese Kis

  • 1Solvo Biotechnology, Budaors, Hungary.

Biological & Pharmaceutical Bulletin
|March 3, 2009
PubMed

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Certain large, lipid-insoluble drug molecules that resemble amino acids, peptides, or glucose, require specialized carrier proteins to facilitate their diffusion across cell membranes. This transport can occur through either facilitated diffusion, which does not require energy input, or active transport, which does require energy input.
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