Three-dimensional imaging of an optic disk pit using high resolution optical coherence tomography
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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Miklos Schneider1, Wolfgang Geitzenauer, Christian Ahlers
1Department of Ophthalmology and Optometry, Medical University Vienna, Vienna - Austria. schneider@szem1.sote.hu
Purpose:
To clarify the origin of the coexisting fluid in an optic disc pit case by using optical coherence tomography (OCT).
Methods:
High resolution OCT (Cirrus prototype, Carl Zeiss Meditec) was used for image acquisition;three dimensional segmentation was performed using Food and Drug Administration-approved imaging software (3D-Doctor V4.0, Able software Corp., Lexington, MA) to demonstrate the structural changes of the optic nerve head and the retina.
Results:
Using high resolution OCT, the authors demonstrated that this case of optic pit had a possible connection between the subretinal and the intraretinal space.
Conclusions:
The authors assume that the intraretinal space is progressively filled with subarachnoidal fluid, leading to a tearing force within the outer neurosensory layers. A connection between the outer nuclear layer and the subretinal space may lead to a serous retinal detachment as a secondary event. Vision loss could consecutively be induced by a serous retinal detachment. High resolution OCT technology is able to visualize discrete changes of the microarchitecture of the optic nerve as well as the retina when combined with appropriate imaging software.
