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Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Related Experiment Video

Updated: Jun 25, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

Registry research in dermatology.

Luigi Naldi1, Liliane Chatenoud

  • 1Centro Studi Gruppo Italiano Studi Epidemiologici in Dermatologia (GISED), Ospedali Riuniti, Largo Barozzi 1, 24100 Bergamo, Italy. luigi.naldi@gised.it

Dermatologic Clinics
|March 4, 2009
PubMed
Summary

Medical registries systematically collect health data. Opportunities exist to create and study dermatology registries for prognosis and disease incidence.

Area of Science:

  • Dermatology
  • Medical Informatics
  • Public Health

Background:

  • A medical registry systematically collects health information on specific conditions.
  • Hospital-based registries focus on patient prognosis.
  • Population-based registries estimate disease incidence in a wider population.

Purpose of the Study:

  • To highlight the importance and potential of establishing medical registries in dermatology.
  • To explore the distinct roles of hospital-based and population-based registries in dermatological research.

Main Methods:

  • Review of the definition and function of medical registries.
  • Analysis of the specific applications for dermatology.
  • Identification of opportunities for registry development in the field.

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Establishment of a Clinic-based Biorepository
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Establishment of a Clinic-based Biorepository

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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Main Results:

  • Medical registries are crucial for systematic health data collection.
  • Dermatology can benefit from both hospital-based (prognosis) and population-based (incidence) registries.
  • Numerous opportunities exist for establishing and investigating these registries in dermatology.

Conclusions:

  • Dermatology has significant potential for developing robust hospital- and population-based registries.
  • These registries can enhance understanding of disease prognosis and incidence.
  • Further investigation and establishment of dermatology registries are warranted.