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[Antimycotic therapy in clinical practice].

A Schaffner1

  • 1Departement für Innere Medizin, Universitätsspital Zürich.

Schweizerische Medizinische Wochenschrift
|September 28, 1991
PubMed
Summary
This summary is machine-generated.

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Common fungal infections in European outpatients are typically superficial and treatable with modern antifungals. Newer azoles simplify treatment for candidiasis, while topical therapies are preferred for dermatophytoses to minimize risks associated with long-term use.

Area of Science:

  • Medical Mycology
  • Pharmacology
  • Infectious Diseases

Context:

  • Focuses on mycoses prevalent in European outpatient settings.
  • Addresses common superficial and mucosal fungal infections.
  • Considers the efficacy and safety of current antifungal agents.

Purpose:

  • To provide an overview of current therapeutic strategies for common mycoses.
  • To guide treatment decisions for candidiasis and dermatophytoses.
  • To highlight safety considerations for systemic antifungal therapies.

Summary:

  • Outpatient mycoses in Europe are generally superficial and responsive to topical or systemic antimycotics.
  • Modern azoles, like fluconazole and itraconazole, offer simplified treatment for mucosal candidiasis.

Related Experiment Videos

  • Topical treatment is recommended for dermatophytoses to limit exposure to newer agents with limited long-term safety data; griseofulvin remains a preferred systemic option for prolonged treatment due to its safety profile.

    • Impact:

    • Informs clinical practice regarding the management of common fungal infections.
    • Emphasizes the importance of selecting appropriate antifungal agents based on infection type and duration.
    • Contributes to patient safety by advising against certain drugs with known hepatotoxicity and limited long-term data.