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Updated: Jun 25, 2026
05:31
Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
Published on: September 20, 2020
[Against CRRT: hybrid treatments are gaining ground]
1Unita' Operativa Complessa di Nefrologia e Dialisi, Ente Ecclesiastico Ospedale Generale Regionale F. Miulli, Acquaviva delle Fonti (Bari), Italy. basile.miulli@libero.it
Summary
Sustained low-efficiency dialysis (SLED) offers a hybrid approach to renal replacement therapies for acute kidney injury in the ICU. This method combines the benefits of intermittent hemodialysis and continuous RRT while mitigating their respective drawbacks.
Area of Science:
- Nephrology
- Critical Care Medicine
- Renal Replacement Therapies
Context:
- Acute kidney injury (AKI) is a common complication in intensive care units (ICUs).
- Renal replacement therapies (RRT) are crucial for managing AKI in critically ill patients.
- Intermittent hemodialysis (IHD) and continuous RRT (CRRT) are standard RRT modalities, each with distinct advantages and limitations.
Purpose:
- To introduce and discuss the concept and benefits of sustained low-efficiency dialysis (SLED) as a hybrid RRT modality.
- To compare SLED with traditional IHD and CRRT in the context of ICU settings.
- To highlight how SLED addresses the limitations of existing RRT methods.
Summary:
- Sustained low-efficiency dialysis (SLED) is presented as an emerging hybrid renal replacement therapy.
- SLED aims to integrate the advantages of both IHD and CRRT.
- This therapy is designed to overcome the disadvantages associated with conventional RRT techniques in the ICU.
Impact:
- SLED offers a potentially more balanced approach to RRT in critical care.
- This modality may provide improved patient outcomes by optimizing fluid and solute management.
- The adoption of SLED could enhance the flexibility and efficacy of AKI treatment in the ICU.
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