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Updated: Jun 25, 2026

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro
Published on: August 28, 2019
Noise-assisted spike propagation in myelinated neurons
Anna Ochab-Marcinek1, Gerhard Schmid, Igor Goychuk
1Institut für Physik, Universität Augsburg, Universitätsstrabetae 1, 86159 Augsburg, Germany and M. Smoluchowski Institute of Physics, Jagellonian University, ul. Reymonta 4, 30-059 Kraków, Poland.
Abstract:
We consider noise-assisted spike propagation in myelinated axons within a multicompartment stochastic Hodgkin-Huxley model. The noise originates from a finite number of ion channels in each node of Ranvier. For the subthreshold internodal electric coupling, we show that (i) intrinsic noise removes the sharply defined threshold for spike propagation from node to node and (ii) there exists an optimum number of ion channels which allows for the most efficient signal propagation and it corresponds to the actual physiological values.
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