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Updated: Jun 25, 2026

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
Published on: August 11, 2016
Perisylvian white matter connectivity in the human right hemisphere
Alireza Gharabaghi1, Frank Kunath, Michael Erb
1Functional and Cognitive Neurosurgery Unit, Department of Neurosurgery and Werner Reichardt Centre for Integrative Neuroscience, University of Tübingen, 72076 Tübingen, Germany. alireza.gharabaghi@uni-tuebingen.de
Background:
By using diffusion tensor magnetic resonance imaging (DTI) and subsequent tractography, a perisylvian language network in the human left hemisphere recently has been identified connecting Brocas's and Wernicke's areas directly (arcuate fasciculus) and indirectly by a pathway through the inferior parietal cortex.
Results:
Applying DTI tractography in the present study, we found a similar three-way pathway in the right hemisphere of 12 healthy individuals: a direct connection between the superior temporal and lateral frontal cortex running in parallel with an indirect connection. The latter composed of a posterior segment connecting the superior temporal with the inferior parietal cortex and an anterior segment running from the inferior parietal to the lateral frontal cortex.
Conclusion:
The present DTI findings suggest that the perisylvian inferior parietal, superior temporal, and lateral frontal corticies are tightly connected not only in the human left but also in the human right hemisphere.
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