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Published on: September 27, 2024

Metabolic syndrome is an independent risk factor for stroke and acute renal failure after coronary artery bypass

Kan Kajimoto1, Katsumi Miyauchi, Takatoshi Kasai

  • 1Department of Cardiovascular Surgery, Juntendo University School of Medicine, Tokyo, Japan.

The Journal of Thoracic and Cardiovascular Surgery
|March 5, 2009
PubMed

Insights

Metabolic syndrome significantly increases the risk of stroke and acute renal failure after coronary artery bypass grafting (CABG). This finding highlights metabolic syndrome as a critical, novel risk factor for adverse outcomes in CABG patients.

Area of Science:

  • Cardiovascular Surgery
  • Metabolic Disorders
  • Nephrology

Background:

  • Metabolic syndrome is prevalent in patients undergoing coronary artery bypass grafting (CABG).
  • The impact of metabolic syndrome on postoperative complications following CABG is not well-established.

Purpose of the Study:

  • To investigate the influence of metabolic syndrome on postoperative outcomes in patients who have undergone CABG.
  • To determine if metabolic syndrome is a significant risk factor for adverse events after CABG.

Main Methods:

  • 1183 patients undergoing CABG were analyzed.
  • Metabolic syndrome was diagnosed using the modified National Cholesterol Education Program Adult Treatment Panel III criteria.
  • Multivariate analysis assessed the association between metabolic syndrome and postoperative complications.

Main Results:

  • Metabolic syndrome was present in 46.6% of patients.
  • Patients with metabolic syndrome had higher rates of postoperative stroke (4.7% vs 2.1%) and acute renal failure (3.8% vs 1.1%).
  • Metabolic syndrome was independently associated with increased odds of stroke (OR 2.47) and acute renal failure (OR 3.81).

Conclusions:

  • Metabolic syndrome is a significant risk factor for postoperative stroke and acute renal failure in CABG patients.
  • Metabolic syndrome should be recognized as a novel risk factor for adverse outcomes in this patient population.
Abstract

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