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Updated: Jun 25, 2026

An Efficient and Rapid HPLC-QQQ-MS Method for the Quantitation of Tropane Alkaloids in Medicinal Plants
Published on: June 12, 2026
[Quality control of non-alkaloids from Radix Sophorae tonkinensis]
Yuan-Yuan Zhang1, Zhi-Yong Guo, Guo-Xiang Xie
1School of Pharmacy, Shanghai Jiaotong University, Shanghai 200240, China. yyzh2035@gmail.com
Objective:
To establish a method for quality control of non-alkaloids from Radix Sophorae tonkinensis.
Methods:
Sugar, organic-acid, polyphenolic and saponin were identified by TLC. The contents of Sugar, polyphenolic and saponin were determined by spectrophotometry and the content of organic-acids was determined by acid-based titration.
Results:
The contents of sugar, polyphenolic and saponin were 54.37%, 4.74%, 4.40%, respectively. The average content of organic-acid was 9.40%.
Conclusions:
The established method is simple, accurate, reproducible and suitable for the quality control of non-alkaloids from Radix Sophorae tonkinensis.
