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HLA class I nucleotide sequences, 1991.

J Zemmour1, P Parham

  • 1Department of Cell Biology, Stanford University, California.

Tissue Antigens
|April 1, 1991
PubMed
Summary
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This compilation presents Human Leukocyte Antigen (HLA) Class I sequences from published literature. It aims to provide an accurate and updated reference for these critical immune system genes.

Area of Science:

  • Immunogenetics
  • Molecular Biology

Background:

  • The Human Leukocyte Antigen (HLA) system is crucial for immune response.
  • Accurate sequence data for HLA alleles is essential for research and clinical applications.

Purpose of the Study:

  • To compile and align Human Leukocyte Antigen (HLA) Class I sequences from existing literature.
  • To resolve discrepancies in reported sequences and ensure data accuracy.

Main Methods:

  • Sequences were gathered from cited publications (Nomenclature for factors of the HLA system, 1990 and 1989).
  • Discrepancies were addressed by contacting original authors for amendments.
  • Sequence alignments were generated, using hyphens for identity, periods for unavailable sequences, and gaps for variations.

Main Results:

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  • A compilation of Human Leukocyte Antigen (HLA) Class I sequences has been established.
  • Amendments were incorporated based on author feedback to improve sequence accuracy.

Conclusions:

  • This compilation serves as a valuable, updated resource for HLA Class I sequences.
  • Ongoing efforts and user-submitted evidence are welcomed to maintain the compilation's accuracy.