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Thrombosis post ovarian hyperstimulation

Saliya Ellen Chipwete¹, Sarah Bugren, Nagy Rafla

¹Women's Health Directorate, Queen Elizabeth the Queen Mother Hospital, Margate, United Kingdom. schipwete@doctors.org.uk

Fertility and Sterility

|March 6, 2009

Abstract

Objective:

To document a rare case of internal jugular and subclavian vein thrombosis following ovarian hyperstimulation syndrome.

Design:

Case report.

Setting:

District General Hospital in the United Kingdom.

Patient(S):

A 37-year-old lady who had undergone in vitro fertilization and subsequently developed internal jugular and subclavian vein thrombosis as a complication of ovarian hyperstimulation syndrome.

Intervention(S):

Treatment with low molecular weight heparin throughout pregnancy.

Main Outcome Measure(S):

Outcome of treatment and the pregnancy.

Result(S):

Successful treatment with a live birth at term.

Conclusion(S):

High index of suspicion for venous thrombosis is needed in women with ovarian hyperstimulation syndrome. Current regimes of prophylactic heparin in these women should be reviewed, as they seem inadequate in preventing thrombosis.

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