Related Experiment Video
Updated: Jun 25, 2026
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Establishment and Analysis of Tumor Slice Explants As a Prerequisite for Diagnostic Testing
Published on: November 29, 2018
Unfinished business: Incomplete laminin processing exposes a tumor target
1Vascular Biology Program, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. jacqueline.banyard@childrens.harvard.edu
Cell Adhesion & Migration
|March 6, 2009
Abstract:
The G45 domain of laminin-332 is cleaved in normal tissues but remains in squamous cell carcinomas. Targeting this domain using a G45 antibody reduced in vivo tumor growth and invasion and suggests a role for G45 as a new therapeutic target.
