Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 25, 2026

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice
06:40

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice

Published on: February 10, 2023

Two-step laparoscopic duodenal switch for superobesity: a feasibility study.

Antonio Iannelli1, Anne Sophie Schneck, Moucef Dahman

  • 1Service de Chirurgie Digestive et Transplantation Hépatique, Hôpital Archet 2, 151 Route Saint Antoine de Ginestiere, BP 3079, 06202, Nice, France. antonio_iannelli@hotmail.com

Surgical Endoscopy
|March 6, 2009
PubMed
Summary

The two-step laparoscopic duodenal switch (LDS) is a safe and effective bariatric surgery for superobese patients, leading to significant weight loss and improved comorbidities with low complication rates.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predictors of 1-year weight maintenance after intragastric balloon removal: a real-world cohort study of 478 patients.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2026
Same author

Metabolic Surgery in the GLP-1 Era: Upfront Toll, Long-Term Dividend.

Obesity (Silver Spring, Md.)·2026
Same author

Predicting Best Performers After Minimally Invasive Left Pancreatectomy: Insights From a National Cohort.

Annals of surgery·2026
Same author

Magnetic Resonance Imaging Systematically Differs from Histology in Quantifying Macrovesicular Liver Steatosis in Individuals with Morbid Obesity: A Prospective Paired MRI-Histology Study in Bariatric Surgery.

Diagnostics (Basel, Switzerland)·2026
Same author

Barrett's Esophagus and Histologic Esophagitis After Laparoscopic Sleeve Gastrectomy: A Long-term Prospective Endoscopic and Histopathologic Evaluation.

Obesity surgery·2026
Same author

The impact of connected devices on postoperative readmission rates after sleeve gastrectomy: a randomized controlled trial.

International journal of surgery (London, England)·2026

Area of Science:

  • Bariatric Surgery
  • Metabolic Surgery
  • Minimally Invasive Surgery

Background:

  • The laparoscopic duodenal switch (LDS) is a complex bariatric procedure.
  • A two-step approach can reduce morbidity and mortality.
  • This strategy identifies patients not needing the second malabsorptive step.

Purpose of the Study:

  • To evaluate the feasibility, safety, and effectiveness of a two-step laparoscopic duodenal switch (LDS).
  • To assess short-term weight loss and comorbidity improvement in superobese patients undergoing the two-step LDS.

Main Methods:

  • Seventy-seven superobese patients initially underwent laparoscopic sleeve gastrectomy.
  • Fifteen patients (19.5%) proceeded to the second step (LDS) due to insufficient weight loss, regain, or persistent comorbidities.

More Related Videos

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
08:50

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

Published on: October 18, 2024

Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

Related Experiment Videos

Last Updated: Jun 25, 2026

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice
06:40

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice

Published on: February 10, 2023

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
08:50

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

Published on: October 18, 2024

Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

  • Data collected included BMI, excess weight loss (%EWL), excess BMI loss (%EBL), and comorbidity status.

    • Main Results:

    • The two-step LDS resulted in significant weight loss: mean BMI decreased from 54 to 33.1 kg/m², with %EWL of 64.6% at 6 months.
    • Comorbidities like hypertension and diabetes showed improvement; one patient's insulin dose decreased significantly.
    • The complication rate was low at 6.7% with no reported deaths.

    Conclusions:

    • The two-step LDS is a feasible, safe, and effective bariatric procedure for superobese individuals.
    • It achieves substantial short-term weight loss and improves comorbid conditions.
    • This staged approach offers a tailored solution for managing severe obesity.