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Updated: Jun 25, 2026
06:51
A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Uncommon benign infantile vascular tumors
Odile Enjolras1, Véronique Soupre, Arnaud Picard
1Centre de Référence des Pathologies Neurovasculaires Malformatives, Site Trousseau, Service de Chirurgie Maxillo-Faciale et Chirurgie Plastique, AP-HP, Hôpital d'Enfants Armand Trousseau, Paris, France. secretariat.enjolras@trs.aphp.fr
Advances in Dermatology
|March 7, 2009
Summary
Recent advances in diagnosing infantile vascular tumors have improved classification and management. Key developments include better understanding of clinical signs, imaging, and GLUT-1 markers, aiding prognosis and treatment.
Area of Science:
- Pediatric Oncology
- Vascular Biology
- Diagnostic Pathology
Background:
- Infantile vascular tumors present diagnostic challenges.
- Accurate diagnosis is crucial for appropriate management and prognosis.
- Past diagnostic methods lacked specificity.
Purpose of the Study:
- To review recent advancements in the diagnosis of infantile vascular tumors.
- To highlight the impact of new diagnostic tools on clinical practice.
- To emphasize improved understanding of tumor behavior and prognosis.
Main Methods:
- Review of clinical characteristics.
- Analysis of radiologic features.
- Histopathologic examination and immunophenotypic marker discovery (e.g., GLUT-1).
Main Results:
- Significant progress in diagnostic accuracy over the past two decades.
- Improved ability to differentiate distinct clinical entities.
- Enhanced understanding of tumor prognosis and invasive potential.
Conclusions:
- Current diagnostic strategies enable clearer classification of infantile vascular tumors.
- Advances facilitate improved management of these lesions.
- Accurate diagnosis is vital for addressing potentially lethal invasive potential.
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