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Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
Published on: September 4, 2017
[Giant cerebral cavernous malformation in a child less than 1 year old: case report]
H Prinzo1, F Martínez, S Carminatti
1Servicio de Neurocirugía Pediátrica. Hospital Pereira Rossell (Ministerio de Salud Pública). Montevideo. Uruguay.
Insights
A rare case of a giant cerebral cavernous malformation in an infant was successfully treated with surgery. This pediatric epilepsy case highlights the importance of early diagnosis and intervention for brain vascular malformations.
Area of Science:
- Neurology
- Pediatric Neurosurgery
- Vascular Neurology
Background:
- Cerebral cavernous malformations (CCMs) are uncommon in pediatric populations.
- Giant CCMs are exceptionally rare in infants, posing diagnostic and therapeutic challenges.
Observation:
- An eleven-month-old boy presented with epilepsy originating at six months of age.
- Magnetic Resonance Imaging (MRI) revealed a large cavernous malformation in the right parietal lobe.
Findings:
- Complete surgical resection of the giant CCM was achieved.
- The patient remained seizure-free postoperatively with over a year of follow-up.
Implications:
- This case underscores the possibility of giant CCMs in infants presenting with epilepsy.
- Early surgical management can lead to favorable outcomes in pediatric patients with brain vascular malformations.
Abstract:
Cerebral cavernous malformations are rarely described in children. Giant cavernous malformations are exceptional in this group of patients. The authors reports a case of an eleven months boy, who begins at the sixth month of life with epilepsy. Medical therapy was advised and imagenological studies were carried out. An IRM was performed, and shows a giant cavernous malformation in the right parietal lobe. Surgery was carried out, with complete resection of the lesion. In the postoperative period and at more than a year of follow up, he was free of crisis. We report the case because of the rarity of a giant cavernous angioma in a patient less than a year old.
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