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Related Concept Videos

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
Arteries of Lower Limbs01:20

Arteries of Lower Limbs

The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular artery,...
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia01:30

Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia

Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...

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Related Experiment Video

Updated: Jun 25, 2026

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice
04:34

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

Published on: January 25, 2022

Femoral nerve blocks.

Renuka Devi Kasibhatla1, Kim Russon

  • 1Royal Hallamshire Hospital, Sheffield Teaching Hospitals.

Journal of Perioperative Practice
|March 10, 2009
PubMed
Summary

Femoral nerve blocks offer safe and effective pain relief after surgery. This method reduces opioid use and its side effects, promoting faster patient recovery and hospital discharge.

Area of Science:

  • Anesthesiology
  • Pain Management
  • Surgical Recovery

Background:

  • Peripheral nerve blocks are increasingly utilized for postoperative pain management.
  • Femoral nerve blocks are a specific type of peripheral nerve block gaining popularity.
  • Effective analgesia is crucial for patient recovery and reducing opioid-related complications.

Purpose of the Study:

  • To highlight the benefits of femoral nerve blocks for lower limb surgery.
  • To emphasize the role of femoral nerve blocks in reducing opioid requirements.
  • To discuss the potential for improved patient mobility and earlier hospital discharge.

Main Methods:

  • Review of existing literature on femoral nerve blocks and peripheral nerve blocks.
  • Analysis of advantages including analgesia quality and opioid-sparing effects.

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The Fibular Nerve Injury Method: A Reliable Assay to Identify and Test Factors That Repair Neuromuscular Junctions
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The Fibular Nerve Injury Method: A Reliable Assay to Identify and Test Factors That Repair Neuromuscular Junctions

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Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice
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Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

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The Fibular Nerve Injury Method: A Reliable Assay to Identify and Test Factors That Repair Neuromuscular Junctions
06:01

The Fibular Nerve Injury Method: A Reliable Assay to Identify and Test Factors That Repair Neuromuscular Junctions

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  • Examination of patient outcomes such as mobilization and discharge timing.

    • Main Results:

    • Femoral nerve blocks provide effective postoperative analgesia for lower limb procedures.
    • Significant reduction in the need for opioids and associated adverse effects (nausea, vomiting, confusion).
    • Potential for earlier patient mobilization and shortened hospital stays.

    Conclusions:

    • Femoral nerve blocks are a valuable tool for postoperative pain control in lower limb surgery.
    • This technique contributes to enhanced patient recovery by minimizing opioid dependency.
    • The benefits extend to improved functional outcomes and efficient healthcare resource utilization.