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Updated: Jun 25, 2026
10:19
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
[Streptococcus B meningitis in infants older than 3 months]
1Réanimation néonatale et pédiatrique, hôpital Armand Trousseau, APHP, Paris 12, France. julia.guilbert@yahoo.fr
Summary
Group B Streptococcus (GBS) meningitis in children over 3 months is less severe than pneumococcal meningitis. This study presents the largest cohort of GBS meningitis in this age group, offering crucial insights into pediatric infectious diseases.
Area of Science:
- Pediatric infectious diseases
- Bacterial meningitis epidemiology
- Streptococcal and pneumococcal infections
Context:
- Bacterial meningitis poses significant risks in childhood, including neurological deficits.
- Group B Streptococcus (GBS) is a primary cause of neonatal sepsis and meningitis.
- Limited data exists on GBS meningitis in pediatric patients beyond the neonatal period.
Purpose:
- To investigate the epidemiology of GBS meningitis in France.
- To compare the clinical presentation and outcomes of GBS meningitis with Streptococcus pneumoniae (PNC) meningitis in children.
- To identify risk factors and clinical characteristics of GBS meningitis in older infants and children.
Summary:
- This study analyzed 17 cases of GBS meningitis and 60 cases of PNC meningitis in children from 2001-2005.
- GBS meningitis cases had a lower gestational age at birth compared to PNC meningitis.
- Neurological complications like seizures and coma were significantly more frequent in PNC meningitis patients.
Impact:
- This research provides the largest published cohort of GBS meningitis in infants over three months old.
- Findings suggest GBS meningitis is less severe than PNC meningitis in this pediatric age group.
- The study contributes to understanding the comparative severity and clinical course of common bacterial meningitis pathogens in children.
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