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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Secondary chronic venous disease progresses faster than primary
Nicos Labropoulos1, Antonios P Gasparis, Dina Pefanis
1Vascular Surgery Division, Stony Brook University Medical Center, Stony Brook, NY 11794-8191, USA. nlabrop@yahoo.com
Journal of Vascular Surgery
|March 10, 2009
Summary
Secondary chronic venous disease (CVD) progresses faster than primary CVD, leading to more skin damage. Early signs of CVD in healthy individuals are rare and slow-progressing.
Area of Science:
- Vascular Medicine
- Venous Thromboembolism
- Chronic Venous Disease
Background:
- Chronic venous disease (CVD) affects a significant portion of the population.
- Distinguishing between primary and secondary CVD is crucial for understanding disease progression.
Purpose of the Study:
- To compare the progression rate of primary chronic venous disease (CVD) versus secondary CVD.
- To identify risk factors associated with advanced CVD progression.
Main Methods:
- A comparative study involving three groups: secondary CVD post-deep vein thrombosis (DVT), primary CVD, and a healthy control group.
- Duplex ultrasound (DU) and clinical examinations were used to assess venous disease severity and progression over 5 years.
- The CEAP classification system was employed to grade disease severity.
Main Results:
- Secondary CVD (post-DVT) showed a significantly higher prevalence and faster progression to skin damage compared to primary CVD and controls.
- Combined reflux and obstruction in proximal veins were identified as significant indicators of advanced CVD progression in secondary CVD.
- Recurrent ipsilateral DVT and multi-segmental venous involvement were associated with poorer outcomes.
Conclusions:
- Secondary CVD exhibits a more rapid progression than primary CVD.
- The combination of reflux, obstruction, recurrent DVT, and multi-segmental involvement are poor prognostic factors for advanced CVD.
- CVD progression in individuals without prior DVT is slow.
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