Cutis Verticis Gyrata Across the Diagnostic Spectrum: Two Cases Highlighting Challenges in Clinical Classification

Area of Science:

• Dermatology
• Clinical Medicine
• Medical Diagnostics

Background:

• Cutis verticis gyrata (CVG) is a rare condition involving cerebriform scalp thickening.
• It can be primary or secondary to systemic disorders, posing classification difficulties.

Purpose of the Study:

• To highlight the diagnostic challenges in classifying Cutis verticis gyrata.
• To illustrate the importance of systematic evaluation for accurate diagnosis.

Main Methods:

• Case report of two patients with distinct CVG presentations.
• Review of clinical findings, ophthalmological, endocrine, and skeletal investigations.

Main Results:

• Patient 1: Progressive scalp thickening and visual impairment, classification uncertain due to loss to follow-up.
• Patient 2: Asymptomatic scalp folds with acne, favored primary essential CVG after normal investigations.

Conclusions:

• CVG classification requires a systematic approach.
• Neurological, ophthalmological, endocrine, skeletal, and dermatological evaluations are essential for definitive diagnosis.