Related Experiment Video
Updated: Jun 25, 2026
05:32
Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
Published on: September 21, 2015
[A serious and unexpected infectious complication after transrectal prostate biopsy]
B V Nguyen1, M Cottrel, B Ralec
1Département d'anesthésie réanimation, hôpital d'instruction des Armées Clermont-Tonnerre, 29200 Brest, France. bavinh@free.fr
Medecine Et Maladies Infectieuses
|March 10, 2009
Summary
Serious Escherichia coli meningitis can occur post-prostate biopsy despite antibiotic use. Fluoroquinolone resistance and bacterial brain barrier crossing may contribute to this rare infectious complication.
Area of Science:
- Infectious Diseases
- Urology
- Microbiology
Background:
- Antimicrobial prophylaxis is standard for preventing surgical site infections.
- Prostate biopsy is a common urological procedure with a low risk of infectious complications.
Observation:
- A rare case of meningitis caused by Escherichia coli is reported following a prostate puncture biopsy.
- The patient did not present with typical risk factors for severe infections.
Findings:
- The development of meningitis suggests potential breaches in standard antimicrobial prophylaxis protocols.
- Factors such as fluoroquinolone resistance in Escherichia coli and its enhanced ability to penetrate the blood-brain barrier may have played a role.
Implications:
- This case highlights the need to consider rare but serious infectious complications after prostate biopsies.
- It underscores the importance of monitoring antimicrobial resistance patterns and understanding bacterial virulence factors in post-procedural infections.
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