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Updated: Jun 25, 2026

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
Falls, faints, fits and funny turns
Roland D Thijs1, Bastiaan R Bloem, J Gert van Dijk
1Dept. of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Postal Zone J03-R, 9600, 2300 RC Leiden, The Netherlands. r.d.thijs@lumc.nl
Abstract:
In this practically oriented review, we will outline the clinical approach of patients with falls due to an impairment or loss of consciousness. Following a set of definitions, we describe the salient clinical features of disorders leading to such falls. Among falls caused by true loss of consciousness, we separate the clinical characteristics of syncopal falls (due to reflex syncope, hypovolemia, orthostatic hypotension or cardiac syncope) from falls due to other causes of transient unconsciousness, such as seizures. With respect to falls caused by an apparent loss of consciousness, we discuss the presentation of cataplexy, drop attacks, and psychogenic falls. Particular emphasis will be laid upon crucial features obtained by history taking for distinguishing between the various conditions that cause or mimic a transient loss of consciousness.
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