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Updated: Jun 25, 2026
Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation
Published on: May 23, 2025
Full-face treatments with the 2790-nm erbium:YSGG laser system
E Victor Ross1, Michael Swann, Seaver Soon
1Dermatology Division, Scripps Clinic, San Diego, CA 92130, USA. Ross.Edward@scrippshealth.org
Background:
Traditional full-face resurfacing has been limited to erbium-doped yttrium aluminium garnet (Er:YAG) and carbon dioxide (CO2) lasers. These devices offer wavelength-specific advantages and disadvantages.
Methods:
Nine patients were enrolled in a pilot study of a resurfacing system using a 2790-nm erbium:yttrium-scandium-gallium-garnet (Er:YSGG) laser system. Two treatments were carried out 1 month apart over the entire face. Test spots were performed prior to the full-face sessions to determine the optimal fluence for 1-pass laser resurfacing. Biopsies were performed at the time of treatment and at the final follow-up visit one month after the second treatment. Clinical endpoints included changes in pigment dyschromias, wrinkles, and skin tone. All outcomes were graded by blinded observers.
Results:
Eight patients completed the 2 treatments. Biopsies showed thermal damage extending as deep as 80 microm below the stratum corneum. Reepithelialization was complete within 4 days. No scarring, post inflammatory hyperpigmentation (PIH), or infections were observed.
Conclusion:
A 2790-nm laser can be used for skin rejuvenation with a 4 day recovery window.
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