[The reaction of the thyroid in the frog Rana temporaria to arginine-vasotocin administration]

Using morphometric technique, it has been shown that single and especially three successive injections of a hypothalamic nonapeptide neurohormone, arginin-vasotocin (5.10(-9) M/kg of body weight) affect functional activity of the thyroid gland in sexually mature male frogs which had been subjected to hypophysectomy 10 or 60 days before neurohormonal treatment. These data presumably confirm a hypothesis about the direct para-adenohypophysial influence of the hypothalamic nonapeptide neurohormone on the peripheral endocrine glands, particularly, the thyroid one.