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Interstitial lung disease and sleep: What is known?
Shikhar Agarwal1, Brittany Richardson, Vidya Krishnan
1Cleveland Clinic, OH, United States.
Sleep Medicine
|March 11, 2009
Summary
Pulmonary fibrosis (PF) patients experience altered sleep architecture, including less REM sleep and more fragmentation. Further research is needed to understand sleep disturbances like obstructive sleep apnea (OSA) in PF.
Area of Science:
- Pulmonary Medicine
- Sleep Science
Background:
- Pulmonary fibrosis (PF) is a progressive lung scarring disorder affecting over 500,000 Americans.
- Fatigue is a common and disabling symptom in PF patients, with prior work noting poor subjective sleep quality.
Purpose of the Study:
- To review and summarize existing literature on sleep and sleep disorders in patients diagnosed with pulmonary fibrosis.
Main Methods:
- A systematic review of English language literature was conducted.
- Studies focusing on sleep and sleep disorders in PF patients were included.
Main Results:
- The literature on sleep in PF is limited and heterogeneous.
- PF is associated with decreased REM sleep and increased sleep fragmentation.
- Potential sleep disturbances, such as obstructive sleep apnea (OSA), are suggested but require further investigation regarding frequency and predictors.
Conclusions:
- Larger studies are crucial to characterize sleep patterns in patients with defined PF.
- Understanding sleep disturbances is critical due to limited therapeutic options for PF and the significant impact of fatigue.
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