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Updated: Jun 25, 2026

Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds
Published on: October 29, 2015
Drug targets in rhinoviral infections
1University Hospital Bergmannsheil, Medical Clinic III, Department of Pneumology, Allergology and Sleep Medicine, Ruhr-University Bochum, Germany. gernot.rohde@ruhr-uni-bochum.de
Abstract:
Human Rhinoviruses (HRV) are by far the most common respiratory viruses responsible for most cases of the common cold and important pathogens in acute exacerbations of asthma and COPD. The molecular pathogenesis of HRV infection is quite completely understood. However there is still no approved specific treatment against HRV infections. The aim of this article is therefore to give an overview of the principles of rhinovirus infection, the associated therapeutic targets and to review up-to-date virus-specific clinical trials.
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