Related Experiment Video
Updated: Jun 24, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[Bone tumor frequency in adults and elderly]
Eréndira G Estrada-Villaseñor1, José F Flores-Carmona, Ernesto Andrés Delgado-Cedillo
1Depto. de Anatomía Patológica, Instituto Nacional de Rehabilitación, Calzada México Xochimilco Núm. 289, Col. Arenal de Guadalupe, Delegación Tlalpan, C. P. 14389, DF México. eestrada@inr.gob.mx
Introduction:
We consider of great importance knowing the types of bone tumors and tumor-like lesions in adults and the elderly, which are increasing in proportion in our country.
Objectives:
(1) To analyze the frequency of bone tumors and tumor-like lesions in adults and elderly; (2) to determine any difference between these two groups; (3) and to analyze the most frequent sites of involvement.
Material And Methods:
We conducted a cross-sectional descriptive study that consisted in a retrolective review of all cases classified as a bone tumor or a tumorlike condition from year 2000-2006. We included all patients that presented with a bone tumor or tumor-like condition above 40 years-old.
Results:
The most frequent diagnoses in patients between 40 and 60 years-old were plasmocytoma/myeloma (19.4%); giant cell tumor (14.1%) and metastases (12.3%). In patients older than 60 years, prevalence of bone tumor and tumor-like lesion was respectively: metastases (37.2%); plasmocytoma/myeloma (11.8%) and malignant fibrous histiocytoma (6.7%). Several differences were observed between these two groups.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
The Effect of Aging on Tissues
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Drug Dosing: Geriatric Patients
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

