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Related Concept Videos

Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
Antimicrobial Proteins01:23

Antimicrobial Proteins

Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Asepsis01:28

Asepsis

The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.

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Related Experiment Video

Updated: Jun 24, 2026

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
06:18

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

Published on: March 3, 2023

Antimicrobial agents for surgical infections.

Nilam P Patel1, Mark A Malangoni

  • 1Critical Care, Department of Pharmacy, Cleveland, OH 44109-1998, USA.

The Surgical Clinics of North America
|March 14, 2009
PubMed
Summary

Antimicrobial drugs are crucial for treating surgical infections and preventing them during surgery. Surgeons must carefully select and use these medications to maximize benefits and minimize potential adverse effects.

Area of Science:

  • Surgical infectious disease management
  • Pharmacology in surgery

Background:

  • Antimicrobial drugs are vital in surgical practice for treating infections.
  • They play a key role in perioperative antimicrobial prophylaxis.
  • Appropriate antimicrobial use is a critical surgical skill.

Purpose of the Study:

  • To highlight the importance of antimicrobial drugs in surgical patient care.
  • To emphasize the need for proper selection and judicious use of these agents.

Main Methods:

  • Review of the role of antimicrobial agents in surgical settings.
  • Discussion of indications for treatment and prophylaxis.

Main Results:

  • Antimicrobial drugs are effective for empiric and definitive infection treatment.

Related Experiment Videos

Last Updated: Jun 24, 2026

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
06:18

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

Published on: March 3, 2023

  • They are essential for preventing surgical site infections through prophylaxis.
  • Adverse effects can occur, necessitating careful consideration.
  • Conclusions:

    • Judicious selection and use of antimicrobial drugs are paramount for surgeons.
    • Balancing therapeutic benefits against potential adverse effects is crucial.
    • Indiscriminate use of antimicrobials in surgery should be avoided.