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Updated: Aug 24, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery
Miklosh Bala1, Fausto Catena2, Jeffry Kashuk3
1Director of Acute Care Surgery and Trauma Unit, Department of General Surgery, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem Kiriat Hadassah, POB 12000, 91120, Jerusalem, Israel. rbalam@hadassah.org.il.
Abstract:
Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09-0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains in the range of 50%. Early diagnosis and timely surgical intervention are the cornerstones of modern treatment to reduce the high mortality associated with this entity. The advent of endovascular approaches in parallel with modern imaging techniques is evolving and provides new treatment options. Lastly, a focused multidisciplinary approach based on early diagnosis and individualized treatment is essential. Thus, we believe that updated guidelines from World Society of Emergency Surgery are warranted, in order to provide the most recent and practical recommendations for diagnosis and treatment of AMI.
Insights
Acute mesenteric ischemia (AMI) is a rare but deadly condition where blood supply to the intestine is interrupted. Early diagnosis and treatment are crucial to reduce high mortality rates.
Area of Science:
- Gastroenterology
- Vascular Surgery
- Emergency Medicine
Background:
- Acute mesenteric ischemia (AMI) involves interrupted blood supply to the intestine, causing ischemia and inflammation.
- Untreated AMI can lead to intestinal necrosis and has a high mortality rate, especially in older patients.
- Despite low incidence, AMI requires prompt attention due to its severe consequences.
Purpose of the Study:
- To highlight the critical need for early diagnosis and timely intervention in managing AMI.
- To emphasize the evolving role of endovascular techniques and advanced imaging in AMI treatment.
- To advocate for updated guidelines from the World Society of Emergency Surgery for AMI diagnosis and management.
Main Methods:
- Review of current literature and clinical practices regarding Acute Mesenteric Ischemia.
- Analysis of diagnostic challenges and treatment modalities, including surgical and endovascular approaches.
- Assessment of the impact of multidisciplinary care and the need for updated clinical guidelines.
Main Results:
- AMI is an uncommon surgical admission but carries a significant mortality risk (up to 50% if untreated).
- Mortality increases with age, and early diagnosis is paramount for effective treatment.
- Endovascular techniques and advanced imaging offer new therapeutic avenues.
Conclusions:
- A multidisciplinary approach focusing on early diagnosis and individualized treatment is essential for AMI.
- Updated guidelines are necessary to provide current, practical recommendations for AMI diagnosis and management.
- Timely surgical intervention remains a cornerstone of treatment to improve patient outcomes.
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