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Sleep associated gas exchange abnormalities in children and adolescents with habitual snoring

Margaret-Ann Carno1, Joseph Modrak, Renee Short

  • 1University of Rochester, Rochester, New York, USA. margaret_carno@urmc.rochester.edu

Pediatric Pulmonology
|March 14, 2009
PubMed

Insights

Obstructive sleep apnea (OSA) is common in children with habitual snoring. Obesity independently worsens sleep-related breathing and gas exchange abnormalities, even after accounting for OSA severity.

Area of Science:

  • Pediatric Sleep Medicine
  • Respiratory Physiology

Background:

  • Habitual snoring in children can indicate underlying sleep-disordered breathing.
  • Obesity is a growing concern in pediatric populations and may impact respiratory health during sleep.

Purpose of the Study:

  • To determine the prevalence of polysomnographically diagnosed obstructive sleep apnea syndrome (OSAS) in children with habitual snoring.
  • To assess the severity of sleep-associated gas exchange abnormalities (SAGEA) in relation to obesity and OSAS severity.

Main Methods:

  • Retrospective chart review of 114 children and adolescents referred for habitual snoring.
  • Analysis of nocturnal polysomnography (NPSG) data, including apnea-hypopnea index (AHI), BMI z-scores, and measures of hypercapnia and oxyhemoglobin desaturation.

Main Results:

  • A high prevalence of OSAS was observed in children with habitual snoring.
  • Increased BMI z-scores positively correlated with OSAS severity, hypercapnia, and oxyhemoglobin desaturation.
  • SAGEA severity increased with progressive obesity, independent of OSAS severity.

Conclusions:

  • OSAS is highly prevalent in children with habitual snoring across various weight categories.
  • Obesity is an independent risk factor for SAGEA in children, even when controlling for OSAS severity.
  • Capnography during NPSG is recommended for obese children with SAGEA.
Abstract

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