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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.

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Related Experiment Video

Updated: Jun 24, 2026

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination
10:32

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination

Published on: August 24, 2015

The current infectious risks of transfusions.

Andreia Marques1, Susan Torres, John Mihran Davis

  • 1Department of Surgery, Robert Wood Johnson Medical School, New Jersey, USA.

Surgical Infections
|March 17, 2009
PubMed
Summary
This summary is machine-generated.

Blood transfusions are safer now due to advanced testing, but emerging infectious agents like viruses and protozoans still pose a risk to blood supply safety. Vigilance against new threats is crucial for maintaining safe transfusions.

Related Experiment Videos

Last Updated: Jun 24, 2026

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination
10:32

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination

Published on: August 24, 2015

Area of Science:

  • Transfusion Medicine
  • Infectious Diseases
  • Public Health

Background:

  • Historically, blood transfusions were a significant route for human immunodeficiency virus (HIV) transmission before 1985.
  • Current blood screening methods offer high sensitivity for HIV and hepatitis C, greatly enhancing blood safety.
  • Emerging infectious agents continually present new challenges to the safety of the blood supply.

Purpose of the Study:

  • To review current and potential infectious agent threats to blood transfusion safety.
  • To assess the evolving landscape of transfusion-transmitted infections.

Main Methods:

  • Systematic review of English language literature.
  • Analysis of historical and current data on transfusion-transmitted infections.

Main Results:

  • Transmission of infectious agents via blood transfusion is infrequent.
  • Protozoans represent a significant threat due to lack of reliable detection assays and global travel.
  • Viruses, such as West Nile virus, and prions have been transmitted through blood transfusions.
  • Emerging threats like SARS, while posing a risk, have not been documented as transfusion-transmitted.

Conclusions:

  • While the current risk of transfusion-transmitted infection is low, potential threats from various infectious agents persist.
  • Continuous monitoring and adaptation of screening protocols are essential to mitigate emerging risks to blood safety.