Successful outcome after prenatal treatment of a cardiac diverticulum with massive pericardial effusion
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Updated: Jun 15, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Khalil Abi-Nader1, Anna L David, Robert Yates
1Fetal Medicine Unit, Elizabeth Garrett Anderson and Obstetric Hospital, University College London Hospitals NHS Foundation Trust, London, UK. k.nader@ucl.ac.uk
Insights
Congenital ventricular cardiac diverticula, a rare condition, can cause fetal pericardial effusion. This case study highlights a successful intervention for massive pericardial effusion, improving fetal outcomes.
Area of Science:
- Cardiology
- Fetal Medicine
- Pediatric Surgery
Background:
- Congenital ventricular cardiac diverticula are rare cardiac malformations.
- These can present prenatally with fetal pericardial effusion, potentially impacting fetal development.
- Management is challenging due to variable disease progression and outcomes.
Observation:
- A case of congenital ventricular cardiac diverticulum with massive fetal pericardial effusion is presented.
- The effusion significantly threatened fetal circulatory and lung development.
- Intervention was performed relatively late in gestation.
Findings:
- Successful pericardiocentesis was performed, leading to a positive fetal outcome.
- The intervention managed the massive pericardial effusion effectively.
- Review of literature and discussion of management options are included.
Implications:
- This case demonstrates the feasibility of late-gestation intervention for fetal pericardial effusion.
- Successful management can improve outcomes in complex congenital cardiac conditions.
- Further research into optimal timing and techniques for intervention is warranted.
Abstract:
Congenital ventricular cardiac diverticula are rare. They may occur prenatally in association with a pericardial effusion which, if large enough, can compromise fetal circulatory and lung development. Parental counseling is difficult because some cases resolve in the second trimester and others progress to worsening hydrops and intrauterine death. We present a case associated with a massive pericardial effusion that had a good outcome after successful pericardiocentesis relatively late in gestation considering the time of critical pulmonary development. We also review similar cases presented in the literature and discuss management options.
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