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Updated: Jun 24, 2026

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Published on: September 14, 2019

Donovanosis.

Paulo Eduardo Neves Ferreira Velho¹, Elemir Macedo de Souza, Walter Belda Junior

¹Division of Dermatology, Campinas University, Campinas, SP, Brazil. pvelho@unicamp.br

The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases

|March 17, 2009

Summary

This summary is machine-generated.

Donovanosis, a chronic bacterial sexually transmitted infection (STI), is underdiagnosed globally. Current diagnostic methods are often hindered by prior antibiotic use, necessitating updated medical knowledge on this tropical disease.

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Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions

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Published on: August 12, 2010

Area of Science:

Infectious Diseases
Bacteriology
Tropical Medicine

Background:

Donovanosis is a chronic bacterial sexually transmitted infection (STI).
It is frequently underdiagnosed in endemic regions and areas with limited experience in tropical diseases.
Syndromic management of STIs and prior antibiotic use complicate diagnostic confirmation.

Purpose of the Study:

To update medical professionals on Donovanosis diagnosis and management.
To highlight challenges in identifying Donovan bodies in cytodiagnostic and histopathological examinations.
To emphasize the need for accessible diagnostic technologies.

Main Methods:

Review of diagnostic challenges for Donovanosis.
Discussion of limitations in cytodiagnostic and histopathological exams.
Exploration of advanced diagnostic technologies.

Main Results:

Donovan bodies are difficult to detect due to syndromic STI treatment and antibiotic use.
Routine diagnostic methods are often insufficient for confirming Donovanosis.
Specialized or advanced technologies may be required for accurate diagnosis.

Conclusions:

Medical professionals require updated information on Donovanosis.
Improved diagnostic strategies and accessibility are crucial for effective management.
Raising awareness is key to addressing the underdiagnosis of this infection.