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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

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Published on: June 2, 2014

Preventive migraine treatment.

Stephen D Silberstein1

  • 1Department of Neurology, Jefferson Headache Center, Thomas Jefferson University Hospital, 111 South Eleventh Street, Gibbon Building, Suite 8130, Philadelphia, PA 19107, USA. stephen.silberstein@jefferson.edu

Neurologic Clinics
|March 18, 2009
PubMed
Summary
This summary is machine-generated.

Migraine treatment includes acute and preventive drugs. Effective preventive options include amitriptyline, divalproex, topiramate, and beta-blockers, with choices considering efficacy, side effects, and patient comorbidities.

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Area of Science:

  • Neurology
  • Pharmacology
  • Internal Medicine

Background:

  • Migraine management involves acute and preventive pharmacologic strategies.
  • Frequent, severe headaches often necessitate a combination of both treatment approaches.

Purpose of the Study:

  • To outline the principles of pharmacologic migraine treatment.
  • To identify effective preventive migraine medications and factors influencing their selection.

Main Methods:

  • Review of established and emerging pharmacologic treatments for migraine.
  • Consideration of drug efficacy, adverse events, patient-specific factors, and comorbidities.

Main Results:

  • Key preventive medications with documented efficacy include amitriptyline, divalproex, topiramate, and beta-blockers.
  • Treatment selection requires balancing drug effectiveness, side effect profiles, patient preferences, and coexisting medical or psychologic conditions.

Conclusions:

  • Optimal migraine pharmacotherapy integrates acute and preventive approaches.
  • Comorbidity significantly influences the choice of preventive medication, potentially impacting treatment outcomes for both migraine and coexisting disorders.