Related Experiment Video
Updated: Jun 24, 2026

14:18
Dioscin Mediated IgA Nephropathy Alleviation by Inhibiting B Cell Activation In Vivo and Decreasing Galactose-Deficient IgA1 Production In Vitro
Published on: October 13, 2023
Ganoderic acid DM: anti-androgenic osteoclastogenesis inhibitor
Jie Liu1, Jun Shiono, Kuniyoshi Shimizu
1Department of Forest and Forest Products Science, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
Bioorganic & Medicinal Chemistry Letters
|March 18, 2009
Abstract:
Prostate cancer is the most common cancer in men in Western countries, with a high incidence of bone metastasis. Ganoderic acid DM, with 5alpha-reductase inhibitory and androgen receptor (AR) binding activity, isolated from the ethanol extracts of Ganoderma lucidum, can inhibit prostate cancer cell growth and block osteoclastogenesis.

