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Updated: Jun 24, 2026

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
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Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

High-throughput and combinatorial technologies for tissue engineering applications.

Anthony Peters1, Darren M Brey, Jason A Burdick

  • 1Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Tissue Engineering. Part B, Reviews
|March 18, 2009
PubMed
Summary
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High-throughput technologies accelerate tissue engineering research by enabling rapid synthesis and characterization of materials. These advanced methods speed up the discovery of novel materials and molecules for tissue repair and stem cell differentiation.

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Translational Research

Background:

  • Tissue engineering requires innovative technologies to accelerate the development of repair strategies for damaged tissues.
  • Traditional iterative methods are insufficient for the rapid identification of novel materials and molecules.

Purpose of the Study:

  • To highlight the role of high-throughput and combinatorial technologies in advancing tissue engineering.
  • To showcase how these technologies facilitate the discovery of new materials and molecules for tissue repair and cell behavior modulation.

Main Methods:

  • High-throughput synthesis and characterization of polymers.
  • Microarray and microfluidic devices for assessing cell-material interactions in 2D and 3D.
  • Small molecule screening for identifying compounds that control cell behavior, including stem cell differentiation.

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Last Updated: Jun 24, 2026

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

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Published on: August 11, 2017

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Published on: September 27, 2019

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Main Results:

  • Diverse technologies enable rapid material synthesis and property characterization.
  • Efficient assessment of cell-material interactions and soluble factor combinations.
  • Identification of molecules influencing stem cell differentiation and other cell behaviors.

Conclusions:

  • High-throughput technologies are crucial for accelerating tissue engineering research and discovery.
  • These methods move beyond traditional approaches to identify unique materials and molecules.
  • Future advancements may enable rapid in vivo screening, further translating findings.