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Clinical approach to clinical herbal toxicity
1Medical College of Wisconsin, Wisconsin Poison Center, Milwaukee, Wisconsin, USA. rtovar@infinityhealthcare.com
Seminars in Diagnostic Pathology
|March 19, 2009
Summary
This review examines the history and current use of herbs in the United States, detailing their clinical effects, side effects, and toxicity. It also covers the treatment of adverse reactions from herbal medicine.
Area of Science:
- Herbal medicine
- Integrative medicine
- Pharmacology
Background:
- Herbal remedies have a long history of use in traditional medicine.
- The use of herbs in the United States has seen a resurgence in recent years.
- Understanding the safety and efficacy of herbal products is crucial for public health.
Purpose of the Study:
- To provide a comprehensive review of the history and current status of herbs in the United States.
- To critically evaluate the clinical effects of herbs and herbal medicine, focusing on potential side effects and toxicity.
- To outline treatment strategies for managing herbal toxicity.
Main Methods:
- Literature review of historical texts and contemporary scientific publications.
- Analysis of clinical data on the efficacy and adverse events associated with herbal medicine.
- Synthesis of information on the pharmacological actions and toxicological profiles of commonly used herbs.
Main Results:
- Herbal medicine use is widespread in the US, with varying regulatory oversight.
- Clinical effects range from beneficial to toxic, depending on the herb, dosage, and individual factors.
- Significant herb-drug interactions and idiosyncratic toxicities have been documented.
Conclusions:
- While herbs offer potential therapeutic benefits, their use requires careful consideration of safety and evidence.
- Further research is needed to establish standardized guidelines for herbal medicine use and to clarify toxicological mechanisms.
- Healthcare providers should be knowledgeable about herbal products to guide patients and manage potential toxicity effectively.
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