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Updated: Jun 24, 2026
07:52
Remote Limb Ischemic Preconditioning: A Neuroprotective Technique in Rodents
Published on: June 2, 2015
[Severe peripheral ischemia of rare origin]
1Université de Médecine et Pharmacie "Gr.T. Popa" Iaşi, IIl-ème Clinique de Chirurgie.
Summary
This case study highlights a rare instance of acute peripheral ischemia in a young patient, potentially linked to temporal arteritis despite a negative biopsy. Corticosteroid treatment proved effective, suggesting this diagnosis.
Area of Science:
- Vascular Surgery
- Rheumatology
- Pathology
Background:
- Acute peripheral ischemia is a serious complication following orthopedic surgery.
- Temporal arteritis (Horton's disease) is an inflammatory condition typically affecting older adults.
Observation:
- A young patient presented with acute peripheral ischemia after lower limb orthopedic surgery.
- Clinical findings suggested Horton arteritis, but the temporal artery biopsy was negative.
- Potential contributing factors included local trauma and medication (ergot derivatives, antibiotics).
Findings:
- Despite negative biopsy, clinical presentation and response to treatment indicated temporal arteritis.
- Corticosteroid therapy led to significant clinical improvement, supporting the diagnosis of temporal arteritis.
Implications:
- This case expands the understanding of potential age-related atypical presentations of temporal arteritis.
- Highlights the importance of considering temporal arteritis in young patients with unexplained peripheral ischemia post-surgery.
- Emphasizes the role of clinical suspicion and treatment response in diagnosing challenging cases.
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