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A rare trifocal presentation of Clostridium septicum myonecrosis
Brent M Wiersema1, D Kevin Scheid, Telly Psaradellis
1Great Lakes Orthopedic Center, Munson Medical Center, 4045 W Royal Dr, Traverse City, MI 49684, USA.
Abstract:
Gas gangrene or clostridial myonecrosis is a rare, life threatening infection of the muscle that is typically associated with recent surgery or trauma. It usually affects older individuals who suffer from vascular insufficiency or who are immunocompromised. The typical pathogen is Clostridium perfringens. Atraumatic gas gangrene caused by Clostridium septicum is less common and has a unique association with colon cancer. This condition aggressively spreads through the muscular tissue and often culminates in septic shock. Fatality occurs within 48 hours if left untreated yet, despite emergent treatment the mortality rate is >50% without any comorbidities. Given the propensity to occur in the extremities the orthopedic surgeon must be familiar with its presentation, diagnosis, and treatment. This article presents a case of a 16-year-old girl who presented to the emergency room with an 18-hour history of malaise and progressive right arm discomfort and swelling. The identification and emergent treatment of necrotizing soft tissue infections is important and often falls on the orthopedic surgeon, especially when isolated to the extremities. Subtle initial presentation and rapid progression of the infection are classic findings of necrotizing soft tissue infections, particularly with clostridial myonecrosis and necrotizing fasciitis. Clostridium myonecrosis is a rare orthopedic condition with high mortality. Early diagnosis and debridement is imperative. A team approach to managing these patients postoperatively is necessary. The use of hyperbaric oxygen can be considered, however, it may not be readily available and its use is unproven in human studies. Due to its high mortality, one should err on the side of more aggressive resective/ablative surgery.
Insights
Gas gangrene, a severe muscle infection, is a rare but life-threatening condition. Early diagnosis and aggressive surgical debridement are crucial for orthopedic surgeons managing this high-mortality infection.
Area of Science:
- Orthopedics
- Infectious Diseases
- Surgical Pathology
Background:
- Gas gangrene, or clostridial myonecrosis, is a rare, life-threatening muscle infection often linked to surgery or trauma.
- It predominantly affects older individuals with vascular insufficiency or compromised immune systems, with Clostridium perfringens as the typical pathogen.
- Atraumatic gas gangrene, less commonly caused by Clostridium septicum, has a notable association with colon cancer.
Observation:
- The condition spreads aggressively through muscle tissue, frequently leading to septic shock.
- Untreated, fatality can occur within 48 hours; even with emergent treatment, mortality exceeds 50% in patients without comorbidities.
- This case highlights a 16-year-old female presenting with acute right arm swelling and discomfort, illustrating the potential for rapid progression.
Findings:
- Necrotizing soft tissue infections, including clostridial myonecrosis, present subtly initially but progress rapidly.
- Early identification and emergent treatment are critical, often falling under the purview of orthopedic surgeons, especially when infections are extremity-based.
- Clostridium myonecrosis is a rare orthopedic condition characterized by high mortality rates.
Implications:
- Prompt diagnosis and aggressive surgical debridement are imperative for managing clostridial myonecrosis.
- A multidisciplinary team approach is essential for postoperative patient care.
- While hyperbaric oxygen therapy may be considered, its efficacy in human studies is unproven, and aggressive surgical intervention is often prioritized due to the high mortality risk.
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