Related Experiment Video
Updated: Jun 18, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
Treatment of large segmental bone defects with reamer-irrigator-aspirator bone graft: technique and case series
Todd A McCall1, David S Brokaw, Bradley A Jelen
1Orthopedic Clinics of Daytona Beach, 1075 Mason Avenue, Daytona Beach, FL 32117, USA.
Abstract:
Treatment of large segmental defects using conventional autogenous iliac crest bone graft can be limited by volume of cancellous bone and donor site morbidity. The reamer-irrigator-aspirator (RIA) technique allows access to a large volume of cancellous bone graft containing growth factors with potency equal to or greater than autograft material from the iliac crest. The purpose of this study was to evaluate the effectiveness of RIA-harvested autogenous bone graft for treating large segmental defects of long bones.
