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Related Experiment Video

Updated: Jun 24, 2026

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Published on: March 24, 2023

Cortical mapping of naming errors in aphasia.

Julius Fridriksson¹, Julie M Baker, Dana Moser

¹Department of Communication Sciences & Disorders, University of South Carolina, Columbia, SC 29208, USA. jfridrik@sc.edu

Human Brain Mapping

|March 19, 2009

Summary

This study reveals common brain activity patterns in individuals with aphasia, linking specific speech errors like phonemic and semantic errors to distinct brain regions. These findings offer new insights into aphasia

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Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia

Published on: July 2, 2013

Area of Science:

Neuroscience
Speech and Language Pathology
Cognitive Neurology

Background:

Aphasia, characterized by anomia (naming impairment), presents diverse clinical profiles in affected individuals.
While left hemisphere lesions are linked to specific naming errors, the role of preserved brain areas in aphasic speech errors remains under-investigated.

Purpose of the Study:

To investigate the cortical activity in preserved brain areas associated with different types and severities of aphasic speech errors.
To identify commonalities in brain modulation across diverse aphasia profiles.

Main Methods:

Utilized functional magnetic resonance imaging (fMRI) to examine brain activity during speech tasks in persons with aphasia.
Correlated specific speech error types (phonemic, semantic) with patterns of cortical activity.

Main Results:

Phonemic errors were associated with cortical activity in the left posterior perilesional occipital and temporal lobes.
Semantic errors showed a similar pattern of activity, but localized to the right hemisphere.
Identified commonalities in brain modulation across different types and severities of aphasia.

Conclusions:

Specific speech errors in aphasia are associated with common patterns of cortical activity in both left and right hemispheres.
This highlights shared neural mechanisms underlying speech errors despite varied clinical presentations of aphasia.