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Updated: Jun 24, 2026
08:03
Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
Published on: December 1, 2016
[Cancer chemotherapy utilizing nanotechnology]
1General Inpatient Division, National Cancer Center Hospital.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|March 20, 2009
Summary
Nanotechnology offers new ways to treat solid tumors by improving drug delivery. Nano-scale formulations leverage the Enhanced Permeability and Retention (EPR) effect for targeted cancer therapy.
Area of Science:
- Oncology
- Nanotechnology
- Materials Science
Context:
- Cancer diagnosis and treatment are rapidly advancing with nanotechnology.
- Solid tumors present unique challenges for drug delivery.
- The tumor vascular system's characteristics enable targeted delivery strategies.
Purpose:
- To describe nano-scale devices for enhanced cancer treatment.
- To explain the utilization of the Enhanced Permeability and Retention (EPR) effect.
- To review ongoing clinical trials of nanomedicines for cancer.
Summary:
- Nano-scale polymeric formulations are being developed for efficient delivery to solid tumors.
- Liposomal, albumin-bound, and polymer micellar formulations are under clinical investigation.
- Doxorubicin-containing liposomes (Doxyl) are an example of a clinically used nanomedicine.
Impact:
- Nanotechnology-based cancer therapies show promise for improved treatment efficacy.
- Targeted drug delivery systems can potentially reduce side effects.
- Ongoing clinical trials will determine the future of nanomedicine in oncology.
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