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Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

Segmented biopolyurethanes for medical applications.

Doina Macocinschi¹, Daniela Filip, Stelian Vlad

¹Petru Poni Institute of Macromolecular Chemistry, Iasi, Romania. eradro2002@yahoo.com

Journal of Materials Science. Materials in Medicine

|March 20, 2009

Summary

Hydroxypropyl cellulose modification enhances polyurethanes for medical use. This reduces platelet adhesion, making these modified polyurethanes promising biocompatible materials for medical devices.

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Area of Science:

Biomaterials Science
Polymer Chemistry

Background:

Polyurethanes are widely used biomaterials for medical devices due to their tunable properties and compatibility.
Modifying polyurethanes can further enhance their suitability for biomedical applications.

Purpose of the Study:

To modify polyester- and polyether-urethanes with hydroxypropyl cellulose.
To evaluate the impact of hydroxypropyl cellulose on the surface, bulk, and hemocompatibility characteristics of polyurethanes.

Main Methods:

Dynamic contact angle measurements.
Dynamic mechanical analysis and mechanical testing.
In vitro platelet adhesion tests.

Main Results:

Hydroxypropyl cellulose modification altered the surface and bulk properties of polyurethanes.
Platelet adhesion was significantly reduced in polyurethanes modified with hydroxypropyl cellulose.

Conclusions:

Hydroxypropyl cellulose incorporation improves the hemocompatibility of polyurethanes.
Modified polyurethanes demonstrate potential as biocompatible materials for medical devices.