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Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation
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[Fetal cerebral magnetic resonance imaging (MRI). Indications, normal and pathological patterns]
C Falip1, P Hornoy, A E Millischer Bellaïche
1Service de radiologie, hôpital Saint-Vincent-de-Paul, 27, rue du Faubourg-Saint-Jacques, 75679 Paris cedex 14, France.
Revue Neurologique
|March 21, 2009
Summary
Fetal MRI offers superior fetal brain imaging compared to ultrasound, aiding in prognosis assessment. Key indicators for poor neurological outcomes include abnormal brain development, guiding clinical decisions.
Area of Science:
- Neurology
- Medical Imaging
- Obstetrics
Context:
- Fetal MRI is performed post-ultrasound, addressing parental anxiety during pregnancy.
- 1.5 tesla magnets have no documented side effects.
- Fetal MRI provides enhanced visualization of fetal brain structures compared to ultrasound.
Purpose:
- To evaluate the diagnostic and prognostic capabilities of fetal MRI.
- To identify specific fetal brain abnormalities indicative of poor neurological prognosis.
- To determine optimal timing for fetal MRI examinations.
Summary:
- Fetal MRI offers superior contrast and delineation of fetal brain structures, including the brainstem and cerebellum, compared to ultrasonography.
- Poor neurological prognosis is associated with specific findings like absent pontic curvature or diffuse cortical malformations.
- Optimal timing for fetal MRI is between 27-30 weeks gestation, balancing development and technical feasibility.
Impact:
- Fetal MRI aids in informed decision-making regarding pregnancy termination, especially within French regulations.
- It serves as an 'in vivo autopsy' when post-abortion examinations are not feasible.
- Advancements in MRI technology and ongoing research are expected to improve its role in assessing neurological prognosis.
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