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Updated: Jun 24, 2026

Detection of Protein Palmitoylation in Cultured Hippocampal Neurons by Immunoprecipitation and Acyl-Biotin Exchange (ABE)
16:33

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Published on: February 18, 2013

Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity.

Kun Huang1, Shaun Sanders, Roshni Singaraja

  • 1Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
|March 21, 2009
PubMed
Summary

Palmitoyltransferases (PATs) show substrate specificity. Specific regulatory domains outside the DHHC domain determine which proteins, like huntingtin, individual PATs modify via palmitoylation.

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