Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Health Literacy and Mental Health in Adolescents: Parental and Self-Reported Cross-Sectional Data in a Bilingual Region.

Healthcare (Basel, Switzerland)·2026
Same author

Procalcitonin neutralization in sepsis: unresolved effects on mononuclear phagocytes.

Open medicine (Warsaw, Poland)·2026
Same author

Impact of 25% albumin administration on intracranial pressure.

Critical care (London, England)·2026
Same author

Conditional Acceptance and the Optimism-Knowledge Gap: A Scoping Review of Attitudes and Perceptions of Artificial Intelligence in Healthcare in Italy.

Medical sciences (Basel, Switzerland)·2026
Same author

Real-world outcomes of [<sup>177</sup>Lu]Lu-PSMA-I&T in [<sup>18</sup>F]FDG-positive metastatic castration-resistant prostate cancer: factors related to response and survival.

European journal of nuclear medicine and molecular imaging·2026
Same author

Behavioral and Psychosocial Correlates of Gender Differences in Adolescent Mental Health: A Regional Cross-Sectional Study in Northern Italy.

Behavioral sciences (Basel, Switzerland)·2026

Related Experiment Video

Updated: Jun 24, 2026

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
08:54

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells

Published on: May 20, 2020

Thromboembolism in pulmonary artery sarcoma.

Mohsen Farsad1, Patrizia Pernter, Antonio Triani

  • 1Department of Nuclear Medicine, Central Hospital of Bolzano, Bolzano, Italy.

Clinical Nuclear Medicine
|March 21, 2009
PubMed
Summary

Pulmonary artery sarcoma can mimic pulmonary embolism, delaying diagnosis and treatment. Integrated FDG PET-CT can help differentiate malignancy from blood clots in pulmonary artery filling defects.

More Related Videos

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
07:44

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

Published on: March 12, 2018

Related Experiment Videos

Last Updated: Jun 24, 2026

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
08:54

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells

Published on: May 20, 2020

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
07:44

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

Published on: March 12, 2018

Area of Science:

  • Cardiovascular Imaging
  • Oncology
  • Pulmonary Medicine

Background:

  • Pulmonary artery sarcoma is a rare malignancy that can mimic pulmonary thromboembolism (PTE) both clinically and radiologically.
  • Differentiating between sarcoma and PTE based on imaging alone, such as contrast-enhanced CT, is challenging.
  • Patients with pulmonary artery sarcoma may not improve with anticoagulation therapy, a common treatment for PTE.

Observation:

  • A case is presented where pulmonary artery thromboembolism was caused by thrombi formed on a pulmonary artery leiomyosarcoma.
  • Contrast-enhanced CT demonstrated filling defects within the pulmonary artery, which are typical for PTE.
  • Integrated FDG PET-CT was utilized to evaluate the filling defects.

Findings:

  • FDG PET-CT revealed no significant FDG uptake in the main portion of the right main pulmonary artery filling defect, consistent with a non-malignant blood clot.
  • Increased FDG uptake was observed along the posterior wall of the right main pulmonary artery and in the left lower lobar artery, suggesting malignancy.
  • This pattern helped differentiate the tumor-associated thrombus from uncomplicated PTE.

Implications:

  • FDG PET-CT can be a valuable tool in the differential diagnosis of pulmonary artery filling defects, especially when PTE is suspected but clinical or imaging features are atypical.
  • Early and accurate diagnosis of pulmonary artery sarcoma is crucial for timely and appropriate treatment, potentially improving patient outcomes.
  • This case highlights the importance of considering rare malignancies in the differential diagnosis of conditions that mimic more common diseases.