The structural basis for peptide selection by the transport receptor OppA

Ronnie P-A Berntsson1, Mark K Doeven, Fabrizia Fusetti

  • 1Biochemistry Department, Groningen Biomolecular Sciences and Biotechnology Institute & Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands.

The EMBO Journal
|March 21, 2009
PubMed
Summary

Lactococcus lactis OppA protein binds peptides of diverse lengths and compositions. Structural analysis reveals a large cavity and flexible termini enabling this broad binding, with a preference for proline-rich peptides.

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