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Related Experiment Video

Updated: Jun 24, 2026

Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects
07:32

Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects

Published on: September 1, 2016

Vibratory thresholds and mobility in older persons.

Aron S Buchman1, Robert S Wilson, Sue Leurgans

  • 1Rush Alzheimer's Disease Center, Armour Academic Facility, Suite #1038; 600 South Paulina, Rush University Medical Center, Chicago, Illinois 60612, USA. Aron_S_Buchman@rush.edu

Muscle & Nerve
|March 24, 2009
PubMed
Summary
This summary is machine-generated.

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Sensory nerve function, measured by vibratory thresholds, is linked to mobility in older adults. This association remained significant even after accounting for various health factors, highlighting the importance of peripheral nerve health for maintaining elderly mobility.

Area of Science:

  • Neurology
  • Gerontology
  • Biomedical Engineering

Background:

  • Mobility decline in the elderly is a significant public health concern.
  • Peripheral sensory nerve function is hypothesized to play a role in maintaining mobility.
  • Vibratory sensation is a key indicator of peripheral nerve function.

Purpose of the Study:

  • To investigate the relationship between vibratory thresholds and mobility in older adults.
  • To determine if vibratory sensation is associated with specific components of mobility, such as gait and balance.

Main Methods:

  • A cohort of 629 elderly individuals without dementia was assessed.
  • Vibratory thresholds were measured bilaterally at the ankle and toes using a Rydel-Seiffer tuning fork.
  • Mobility was evaluated using 11 lower extremity performance measures and the modified United Parkinson's Disease Rating Scale (UPDRS), summarized into composite mobility and parkinsonian signs scores.

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Related Experiment Videos

Last Updated: Jun 24, 2026

Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects
07:32

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Published on: September 1, 2016

Behavioral Assessment of the Aging Mouse Vestibular System
09:30

Behavioral Assessment of the Aging Mouse Vestibular System

Published on: July 11, 2014

Whole Body Vibration Methods with Survivors of Polio
04:16

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Main Results:

  • Vibratory threshold showed a significant association with composite mobility (P < 0.001) and global parkinsonian signs (P = 0.047) in regression models adjusted for age, sex, and education.
  • The association was primarily driven by gait and balance components of mobility and parkinsonian gait.
  • These findings were robust and persisted after controlling for numerous potential confounders including BMI, physical activity, cognition, depression, vascular factors, and falls.

Conclusions:

  • Vibratory thresholds are significantly associated with mobility in the elderly population.
  • This study supports a link between peripheral sensory nerve function and the maintenance of mobility in older adults.
  • Assessing vibratory sensation may offer insights into mobility impairments and inform interventions for fall prevention and functional independence.