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Interferon alpha in the therapy of CML
M Talpaz1, H Kantarjian, R Kurzrock
1Department of Clinical Immunology and Biological Therapy, University of Texas Cancer Center, M.D. Anderson Hospital, Houston.
British Journal of Haematology
|October 1, 1991
Summary
This study reviews interferon alpha (IFN alpha) treatments, both alone and combined, at M.D. Anderson Cancer Center. It also discusses related laboratory research findings for cancer therapy.
Area of Science:
- Oncology
- Immunotherapy
Background:
- Interferon alpha (IFN alpha) is a cytokine used in cancer treatment.
- Clinical experience with IFN alpha therapy varies and requires comprehensive summary.
Purpose of the Study:
- To summarize clinical experience with interferon alpha (IFN alpha) therapy.
- To present findings from associated laboratory research.
Main Methods:
- Review of clinical data from M.D. Anderson Cancer Center.
- Analysis of laboratory research linked to clinical studies.
Main Results:
- Summarizes single-agent and combination therapy outcomes with IFN alpha.
- Highlights laboratory findings relevant to clinical applications.
Conclusions:
- Interferon alpha (IFN alpha) has been utilized in various therapeutic settings.
- Laboratory research provides insights into IFN alpha's mechanisms and applications.