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Related Concept Videos

Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...

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Updated: Jun 24, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

Pediatric overweight: a weighty mortality concern.

Daniel D Zimmerman1

  • 1Northwestern Mutual Life Insurance Company, 720 E. Wisconsin Avenue, Milwaukee, Wisconsin 53202-4797, USA. danielzimmerman@northwesternmutual.com

Journal of Insurance Medicine (New York, N.Y.)
|March 26, 2009
PubMed
Summary

Pediatric overweight is increasingly impacting child insurance risk assessments. This review examines long-term mortality risks in overweight children and their implications for insurability.

Area of Science:

  • Pediatric Health
  • Public Health
  • Insurance Medicine

Background:

  • Pediatric overweight and obesity are rising public health concerns.
  • Existing literature extensively covers pediatric obesity's causes and treatments.
  • Long-term outcomes and mortality data for overweight children are less explored.

Purpose of the Study:

  • To review mortality risks associated with pediatric overweight.
  • To evaluate the impact of these risks on child insurability.
  • To inform pediatric underwriting and risk stratification processes.

Main Methods:

  • Literature review focusing on mortality studies in overweight children.
  • Analysis of current and projected trends in pediatric overweight.
  • Examination of insurance underwriting guidelines and risk factors.

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Last Updated: Jun 24, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Adult and Pediatric Porcine Model of Acute Volume Overload
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Adult and Pediatric Porcine Model of Acute Volume Overload

Published on: January 12, 2024

Main Results:

  • Increasing prevalence of pediatric overweight presents new challenges for risk assessment.
  • Emerging data suggests potential long-term mortality implications.
  • Underwriting practices are beginning to adapt to these changing risk profiles.

Conclusions:

  • Mortality associated with pediatric overweight requires careful consideration in underwriting.
  • Future insurability of children may be significantly affected by overweight trends.
  • Further research is needed to refine risk stratification for overweight children.